Pharmacotherapy
Clinician's Perspective: • In Singapore, it is estimated that 12.7% of the population has a BMI of 30 or higher, a significant 22.8% of residents fall into the high-risk category (BMI ≥27.5) due to the higher risk of cardiovascular disease in Asian populations. • Healthy diet
Bariatric Endoscopy
Clinician's Perspective: • In patients who have undergone gastric bypass, Transoral Outlet Reduction (TORe) aims to narrow the Gastrojejunal Anastomosis (the surgical connection between the stomach pouch and the small bowel) using endoscopic suturing, slowing down gastric emptying. • High Efficacy: The procedure demonstrated a pooled clinical success rate of
Bariatric Endoscopy
Clinician's Perspective: • Durable Weight Loss: Patients undergoing Transoral Outlet Reduction (TORe) achieve a Total Body Weight Loss (TBWL) of approximately 8.4% at the five-year mark, effectively halting the upward trajectory of weight regain. • TORe focuses on narrowing the Gastrojejunal Anastomosis (the surgical connection between the stomach
Bariatric Endoscopy
Clinician's Perspective: • The procedure involves placing a medical-grade balloon typically made of silicone into the stomach via an endoscope (a flexible tube with a camera), requiring no incisions or general anesthesia. Newer generations of balloons are swallowable and do not require endoscopic insertion. • Significant Weight Reduction: On
Bariatric Endoscopy
Clinician's Perspective: • Gastric Volume Reduction: The procedure utilizes an endoscope to reduce the stomach to a narrow tube, roughly 30% of its original capacity, without external surgical incisions. • Weight Loss Efficacy: Clinical data indicates patients achieve an average weight loss of 15% of their total body weight within
Bariatric Endoscopy
Clinician's Perspective: • The controlled study randomized 40 participants to either Endoscopic Sleeve Gastroplasty (ESG) or a sham (simulated) procedure to isolate the specific impact of the intervention. • Weight Loss Efficacy: Participants in the ESG group achieved a mean total body weight loss (TBWL) of 9.47%, more than
Bariatric Endoscopy
Clinician's Perspective: • Clinical Efficacy: Participants undergoing Endoscopic Sleeve Gastroplasty (ESG) achieved a mean excess weight loss (EWL) of 49.2% at 52 weeks, compared to just 3.2% in the control group. • Metabolic Impact: The data reveals that 80% of the ESG cohort experienced significant improvement in one